NP Thyroid vs Armour Thyroid: What’s the Difference? (2022)

NP Thyroid is a thyroid medication which is similar but slightly different than Armour thyroid.

Will switching from Armour to NP make a difference in your body? Will it help with weight loss? Will it prevent hair loss?

The answer is maybe and it has to do with the difference between these medications.

The difference is not big, but sometimes a small difference can manifest as a large change in your symptoms.

This article will help you decide whether or not you should switch medications.


What is NP Thyroid?

What exactly is NP Thyroid?

NP Thyroid is a relatively new thyroid medication which is available. It has become more popular as it has become harder and harder to get other forms of Natural Desiccated Thyroid medications such as Nature-throid and WP Thyroid.

It's important for you to understand that NP thyroid is another formulation of Natural Desiccated thyroid hormone and medication.

What does that mean?

NP Thyroid vs Armour Thyroid: What’s the Difference? (1)

It means that it contains the same active ingredients as Armour thyroid but it differs in the type and amount of inactive ingredients.

Both medications are considered natural and both are sourced from animal thyroid glands (porcine-derived).

Both Armour thyroid and NP Thyroid are dosed in the same way with equivalent doses.

That means 60mg of Armour thyroid is equal to 60mg of NP Thyroid.

Each grain of NP Thyroid contains 38mcg of T4 thyroid hormone and 9 mcg of T3 thyroid hormone which is similar to other brands and formulations of NDT (*this is also true of Armour thyroid).

Does that mean that you will react the exact same way if you switch medications?

Not exactly and that's part of the point of this article.

In fact, sometimes simply switching from one type of thyroid medication to another (even if it's in the same class of medications) can dramatically improve your symptoms.

Much of this has to do with how your body tolerates the inactive ingredients and how well they are absorbed into your bloodstream from the intestines (1).

NP thyroid has fewer inactive ingredients when compared to Armour thyroid which may influence this absorption.

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(Video) NP Thyroid vs Armour Thyroid: Cost & Ingredient Differences

What's the Difference Between NP Thyroid and Armour Thyroid?

NP thyroid is worth considering especially if you are currently using Armour thyroid due to several important reasons:

#1. It is slightly cheaper when compared to Armour Thyroid.

And #2. It contains fewer inactive ingredients than Armour Thyroid.

The number and type of inactive ingredients found inside of medications are actually quite important because some medications contain starches or plant produces that can cause digestive issues.

Other medications (such as Synthroid) contain lactose products (2) which can cause reactions if you suffer from lactose intolerance!

(Video) Levothyroxine or Armour Thyroid for Hypothyroidism (Low Thyroid Symptoms)

So how does Armour Thyroid differ from NP thyroid?

Ingredient list of Armour Thyroid includes:

Armour thyroid contains 2 active ingredients (thyroid hormones) and 5 inactive ingredients.

The two inactive ingredients that may cause issues for most people include the starch and microcrystalline cellulose.

These can be difficult to digest in some individuals, especially if they suffer from low stomach acid or other digestive issues.

I've had many patients who simply switch from one brand of NDT to another and find that they get almost immediate relief from their symptoms.

This doesn't happen in everyone but it's always worth considering.

NP Thyroid Ingredient List

Ingredient list of NP thyroid includes:

NP thyroid has a total of 2 active ingredients and 4 inactive ingredients. Even though NP and Armour differ only by 1 inactive ingredient that may still cause quite a bit of difference in certain people.

If you react to the inactive ingredients then you may suffer from unexplained side effects such as dizziness, headaches, rashes, stomach pain, gas or bloating after taking your thyroid medication.

These symptoms can be confusing, especially if you aren't sure if you are being dosed correctly, but they may be a sign that you are reacting to the inactive ingredients in your medication.

Cost of NP Thyroid

The cash price of NP thyroid is right around $14 - $15 per month.

Most insurances will cover it but in case yours doesn't you can use a tool like to help reduce the price by using cash coupons.

I generally compare the cash price of medications here so that you get an idea of what they cost on a monthly basis.

The prices of medication will vary slightly based upon your location but it shouldn't be much more than $15 per month of the 30mg tablets (1/2 grain).

NP Thyroid vs Armour Thyroid: What’s the Difference? (3)

How does that compare to Armour Thyroid?

The cash price of Armour thyroid is almost double with a monthly cost of $26 - $27 for a 30 day supply of 30mg tablets.

NP Thyroid vs Armour Thyroid: What’s the Difference? (4)

If you find that your prescription cost is climbing steadily over a period of months to years then it may be a good idea to consider switching from Armour to NP thyroid.

NP Thyroid and Weight Loss

Does NP thyroid cause weight loss and will it help you?

(Video) Armour Thyroid versus Synthroid

The answer is that it really depends.

If you are already on Armour thyroid and interested in switching to NP thyroid then it probably will not help with weight loss significantly.

If, on the other hand, you are taking Synthroid or levothyroxine and you want to switch over then it might help.

Why is that?

It has to do with the thyroid hormone content in each tablet of medication.

NP thyroid contains a combination of both T4 and T3 in the ratios described above.

The real benefit of using these medications stems from the fact that T3 is included in them.

Studies have shown that weight loss, especially in thyroid patients, is heavily influenced by both the free T3 and total T3 levels.

The higher your free T3 and total T3, the more likely you are to not only lose weight but to also keep it off (3).

NP Thyroid vs Armour Thyroid: What’s the Difference? (5)

The easiest way to increase both your free T3 and total T3 is with the use of thyroid medications which contain pure T3.

This includes NP thyroid but also other medications such as Cytomel and liothyronine.

Another strategy to increase your free T3 is by using natural therapies which can help enhance thyroid conversion.

Therapies such as certain supplements, managing inflammation, and taking botanicals can help. I've written about how to do this naturally in this 8 step guide which you can learn more about here.

NP Thyroid Side Effects

All thyroid medications can potentially cause negative side effects.

Most of the time, though, these side effects are self-limiting and dose-dependent.

What does that mean?

It means that if you reduce your dose these side effects tend to go away. And some side effects tend to go away on their own even without manipulating your dose.

The most concerning side effects, from a patient perspective, include increased hair loss and heart palpitations.

Both of these tend to be dose-dependent, but hair loss may be directly related to the medication itself.

If you have hair loss while using NP thyroid then you may need to switch to a different medication entirely as this side effect may not go away.

You can learn more about managing hair loss with thyroid disease here.

Potential side effects of using NP thyroid include:

  • Hair loss
  • Heart palpitations
  • Weight loss
  • Tremors
  • Headaches
  • Diarrhea
  • Migraines
  • Stomach pain

If you experience any of these side effects you should reach out to your prescribing Doctor and get your blood drawn.

More serious but rare side effects on NP thyroid include (usually related to a very high dose):

  • Chest pain
  • Shortness of breath
  • Bone loss
  • Heart enlargement

These side effects are quite rare and tend to occur only in susceptible patients. If you experience any of these then you should seek medical attention immediately.

(Video) VIDEO: Is pig extract a thyroid cure?

Is NP Thyroid Considered Natural or Synthetic?

NP thyroid is considered to be a natural thyroid medication because it is derived from animal thyroid glands.

The hormones contained in this medication were created by the thyroid gland of animals and not in a lab.

Natural thyroid medications (Armour thyroid, Nature-throid, WP thyroid, and NP thyroid) should be differentiated from synthetic medications (Synthroid, levothyroxine, Cytomel, liothyronine, and Tirosint).

Just because NP thyroid is natural does not mean that it is superior to other forms of thyroid medications, however.

Some people do quite well on clean T4 only thyroid medications such as Tirosint, especially when combined with T3 only thyroid medications.

The benefit to using these medications separately is that you can easily titrate your T4 and T3 dose.

If you've tried all of the different types of natural thyroid medications and you still aren't feeling well then you may want to give a cleaner T4 + T3 thyroid medication combination a try.

Final Thoughts and Recommendations

If you are wondering whether or not you should switch from your medication to NP thyroid then I would consider the following questions:

Are you currently happy with your medication? (If the answer is no then you may want to consider switching)

Do you feel that your medication is helping reduce your symptoms? (if the answer is no then you may want to consider switching)

Are you experiencing symptoms which may be related to inactive fillers or binders? (if the answer is yes then you may want to consider switching)

Are you happy with the current price of your medication? (if the answer is no then you may want to consider switching)

Depending on how you answered these questions you may want to consider altering your medication.

As long as you switch our your medication for an equivalent dose (which is easy if you are on Armour thyroid) then there shouldn't be a problem with the transition.

If you don't experience any positive benefit after a 2 month trial on the new medication then you can simply switch back.

But, on the other hand, if you experience a positive change then it may be worth sticking with it.

Not everyone will experience a positive change when or if they switch, but it's always worth a shot, especially when your health is on the line.

Now I want to hear from you:

Are you currently taking NP thyroid?

Are you considering switching from whatever you are taking to NP thyroid?

What is holding you back?

Leave your questions or comments below!

References (Click to Expand)

NP Thyroid vs Armour Thyroid: What’s the Difference? (6)

(Video) Np thyroid: Should you use this thyroid medication? (5 things to know)


NP Thyroid vs Armour Thyroid: What’s the Difference? ›

NP Thyroid is manufactured by Acella Pharmaceuticals, and Armour Thyroid is manufactured by Allergan Pharmaceuticals. Both medicines are available by prescription only. There are two main categories of thyroid replacement therapy: Natural products, which are made from grinding up dried thyroid glands from animals.

Why is Armour Thyroid not recommended? ›

Due to the potential drug interaction between both natural and prescribed thyroid hormone and testosterone supplements, patients should be discouraged from self-administration of thyroid or anabolic steroids. Due to the lack of standardization in the T3 content, the use of Armour Thyroid should be avoided.

What is the most effective thyroid medication? ›

The FDA has approved levothyroxine for the treatment of hypothyroidism. It is the most commonly prescribed form of thyroid replacement, largely because it has the most data to support its use. There are several formulations of levothyroxine, but some brand names include Synthroid, Levoxyl, and Levo-T.

What is the best alternative to Armour Thyroid? ›

  • Levoxyl.
  • Nature-Throid.
  • Cytomel.
  • Tirosint.
  • Liothyronine.
  • Euthyrox.

Which is better Nature-Throid or Armour? ›

Armour Thyroid has an average rating of 6.6 out of 10 from a total of 233 ratings on 55% of reviewers reported a positive effect, while 29% reported a negative effect. Nature-Throid has an average rating of 7.0 out of 10 from a total of 70 ratings on

Is NP thyroid same as Armour Thyroid? ›

Official answer. NP Thyroid and Armour Thyroid are two different brands of natural thyroid hormone tablets. Both products are made using dried ground thyroid glands from pigs and contain a combination of two thyroid hormones, triiodothyronine (T3) and thyroxine (T4) in the same proportion.

What is the best natural thyroid medication? ›

The most pure form of a natural thyroid medication is WP Thyroid used to be called Westhroid Pure. WP Thyroid is gluten and corn free with no artificial colors and only contains three other ingredients inulin (from chicory root), medium chain triglycerides and Lactose Monohydrate.

Does NP thyroid give you energy? ›

About NP Thyroid

They help support metabolism and energy levels.

What is the best medication for underactive thyroid? ›

An underactive thyroid (hypothyroidism) is usually treated by taking daily hormone replacement tablets called levothyroxine. Levothyroxine replaces the thyroxine hormone, which your thyroid does not make enough of. You'll initially have regular blood tests until the correct dose of levothyroxine is reached.

How long does it take for NP thyroid to work? ›

Adequate therapy usually results in normal TSH and T4 levels after 2 to 3 weeks of therapy.

What can I take instead of NP thyroid? ›

Armour Thyroid, Cytomel, Thyrolar, Synthroid, and Levoxyl are some levothyroxine alternatives. Get the full list here. Levothyroxine is a generic thyroid hormone medication used to treat an underactive thyroid (hypothyroidism).

What happens if you take too much NP thyroid? ›

Symptoms of overdose may include: fast/pounding/irregular heartbeat, loss of consciousness, confusion, seizures. Do not share this medication with others. Laboratory and/or medical tests (such as thyroid function tests) should be performed periodically to monitor your progress or check for side effects.

Can Armour Thyroid cause heart problems? ›

Taking too much Armour Thyroid can cause overdose symptoms that include: A racing heart. Chest pain. Shortness of breath.

Why has Armour Thyroid been recalled? ›

The products are being recalled because routine testing has found these lots to be sub potent. The product contains less than 90% of the labeled amount of liothyronine (T3) and/or levothyroxine (T4).

Which is better levothyroxine or Armour Thyroid? ›

Our research shows that patients generally feel better on Armour Thyroid compared to levothyroxine. Armour Thyroid is an effective medication to use for patients who remain symptomatic on levothyroxine and should be considered as a viable option in clinical practice.

Which is better Synthroid or Armour? ›

There is no strong evidence to suggest Armour Thyroid or a combination therapy of synthetic T4 and T3 produce better results than Synthroid in most people (1). More specifically, Synthroid is recommended over Armour Thyroid because it: Efficiently reduces symptoms of hypothyroidism. Has minimal side effects.

What does Armour Thyroid do to your body? ›

Thyroid hormone is used to treat underactive thyroid (hypothyroidism). It is a natural product made from animal thyroid glands (usually a pig's). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland.


1. Thyroid Conversion Chart - Armour thyroid vs Synthroid vs T3
(Dr. Westin Childs)
2. Levothyroxine Vs Armour Thyroid Medication - How Are They Different and Which Is Better?
(Sara Peternell - Everything Hashimoto’s!)
3. Armour thyroid - 10 things you should know BEFORE using it
(Dr. Westin Childs)
4. Natural Desiccated Thyroid: Why Some People React Badly
(Dr. Eric Berg DC)
5. Effectiveness of Thyroid Medications: Mayo Clinic Radio
(Mayo Clinic)
6. Synthetic vs Desiccated Thyroid Medicine
(McCall McPherson)

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